AN ANALYSIS OF ABNORMALITIES IN THE B CELL RECEPTOR REPERTOIRE IN PATIENTS WITH SYSTEMIC SCLEROSIS USING HIGH-THROUGHPUT SEQUENCING

An analysis of abnormalities in the B cell receptor repertoire in patients with systemic sclerosis using high-throughput sequencing

Systemic sclerosis is a chronic multisystem autoimmune disease that is associated with polyclonal B cell hyperreactivity.The CDR3 of BCRs is the major site of antigen recognition.Therefore, we analyzed the BCR repertoire of patients with SSc.The BCR repertoires in 12 subjects including eight SSc patients and four healthy controls were characterized

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Mechanical, fatigue, and superplasticity properties of Cu-Al-Mn, Cu-Al-Be-Mn shape memory alloy and their metal matrix composites

This study explores the characteristics and potential engineering applications of Cu-Al-Mn and Cu-Al-Be-Mn shape memory alloys (SMAs).The research investigates the chemical composition, transformation temperatures, and mechanical properties of these SMAs when incorporated into Al metal matrix composites.It was found that the addition Multiple Vitam

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